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1

Impaired microvascular perfusion in sepsis requires activated coagulation and P-selectin-mediated platelet adhesion in capillaries

Dan Secor, Fuyan Li, Christopher G. Ellis, Michael D. Sharpe, Peter L. Gross, John X. Wilson, Karel Tyml

Journal:

Intensive Care Medicine

Year:

2010

Language:

english

File:

PDF, 367 KB

english, 2010

2

Ascorbate protects against impaired arteriolar constriction in sepsis by inhibiting inducible nitric oxide synthase expression

Feng Wu, John X. Wilson, Karel Tyml

Journal:

Free Radical Biology and Medicine

Year:

2004

Language:

english

File:

PDF, 206 KB

english, 2004

3

Ascorbate inhibits NADPH oxidase subunit p47phox expression in microvascular endothelial cells

Feng Wu, David P. Schuster, Karel Tyml, John X. Wilson

Journal:

Free Radical Biology and Medicine

Year:

2007

Language:

english

File:

PDF, 642 KB

english, 2007

4

Ascorbate prevents microvascular dysfunction in the skeletal muscle of the septic rat

Armour, John, Tyml, Karel, Lidington, Darcy, Wilson, John X.

Journal:

Journal of Applied Physiology

Year:

2001

Language:

english

File:

PDF, 357 KB

english, 2001

5

Endotoxin increases intercellular resistance in microvascular endothelial cells by a tyrosine kinase pathway

Darcy Lidington, Yves Ouellette, Karel Tyml

Journal:

Journal of Cellular Physiology

Year:

2000

Language:

english

File:

PDF, 231 KB

english, 2000

6

Extremely low frequency pulsed electromagnetic field designed for antinociception does not affect microvascular responsiveness to the vasodilator acetylcholine

Julia C. McKay, Michael Corbacio, Karel Tyml, Frank S. Prato, Alex W. Thomas

Journal:

Bioelectromagnetics

Year:

2010

Language:

english

File:

PDF, 261 KB

english, 2010

7

Lipopolysaccharide-induced reductions in cellular coupling correlate with tyrosine phosphorylation of connexin 43

Darcy Lidington, Karel Tyml, Yves Ouellette

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 197 KB

english, 2002

8

Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway

Keeley Rose, Yves Ouellette, Michael Bolon, Karel Tyml

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 201 KB

english, 2005

9

Lipopolysaccharide reduces electrical coupling in microvascular endothelial cells by targeting connexin40 in a tyrosine-, ERK1/2-, PKA-, and PKC-dependent manner

Michael L. Bolon, Gerald M. Kidder, Alexander M. Simon, Karel Tyml

Journal:

Journal of Cellular Physiology

Year:

2007

Language:

english

File:

PDF, 356 KB

english, 2007

10

iNOS expression requires NADPH oxidase-dependent redox signaling in microvascular endothelial cells

Feng Wu, Karel Tyml, John X. Wilson

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 352 KB

english, 2008

11

Lipopolysaccharide plus hypoxia and reoxygenation synergistically reduce electrical coupling between microvascular endothelial cells by dephosphorylating Connexin40

Michael L. Bolon, Tianqing Peng, Gerald M. Kidder, Karel Tyml

Journal:

Journal of Cellular Physiology

Year:

2008

Language:

english

File:

PDF, 301 KB

english, 2008

12

Comparative ultrastructure of Langerhans-like cells in spleens of ray-finned fishes (Actinopterygii)

Jan Lovy, Glenda M. Wright, David J. Speare, Tomas Tyml, Iva Dykova

Journal:

Journal of Morphology

Year:

2010

Language:

english

File:

PDF, 1.30 MB

english, 2010

13

Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition

Jasminka Korcok, Feng Wu, Karel Tyml, Robert R. Hammond, John X. Wilson

Journal:

Journal of Neurochemistry

Year:

2002

Language:

english

File:

PDF, 233 KB

english, 2002

14

Nitric Oxide Attenuates but Superoxide Enhances iNOS Expression in Endotox in- and IFNγ-Stimulated Skeletal Muscle Endothelial Cells

FENG WU, GEDIMINAS CEPINSKAS, JOHN X. WILSON, KAREL TYML

Journal:

Microcirculation

Year:

2001

Language:

english

File:

PDF, 419 KB

english, 2001

15

Critical Role for Oxidative Stress, Platelets, and Coagulation in Capillary Blood Flow Impairment in Sepsis

Journal:

Microcirculation

Year:

2011

Language:

english

File:

PDF, 416 KB

english, 2011

16

Ascorbate Inhibits Reduced Arteriolar Conducted Vasoconstriction in Septic Mouse Cremaster Muscle

REBECCA L. MCKINNON, DARCY LIDINGTON, KAREL TYML

Journal:

Microcirculation

Year:

2007

Language:

english

File:

PDF, 1013 KB

english, 2007

17

Abrupt Reoxygenation of Microvascular Endothelial Cells After Hypoxia Activates ERK1/2 and JNK1, Leading to NADPH Oxidase-Dependent Oxidant Production

GUO YU, TIANQING PENG, QINGPING FENG, KAREL TYML

Journal:

Microcirculation

Year:

2007

Language:

english

File:

PDF, 1.80 MB

english, 2007

18

Role of connexins in microvascular dysfunction during inflammation

Journal:

Canadian Journal of Physiology and Pharmacology

Year:

2011

File:

PDF, 450 KB

2011

19

Reduction of electrical coupling between microvascular endothelial cells by NO depends on connexin37

McKinnon, R. L., Bolon, M. L., Wang, H.-X., Swarbreck, S., Kidder, G. M., Simon, A. M., Tyml, K.

Journal:

AJP Heart and Circulatory Physiology

Year:

2009

Language:

english

File:

PDF, 876 KB

english, 2009

20

Hypoxia and reoxygenation-induced oxidant production increase in microvascular endothelial cells depends on connexin40

Guo Yu, Michael Bolon, Dale W. Laird, Karel Tyml

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 584 KB

english, 2010

21

Evaluation of Pulsatile and Nonpulsatile Flow in Capillaries of Goat Skeletal Muscle Using Intravital Microscopy

John J. Lee, Karel Tyml, Alan H. Menkis, Richard J. Novick, F.Neil McKenzie

Journal:

Microvascular Research

Year:

1994

File:

PDF, 456 KB

1994

22

Microvascular Response to Ischemia, and Endothelial Ultrastructure, in Disused Skeletal Muscle

Karel Tyml, Odile Mathieu-Costello, Earl Noble

Journal:

Microvascular Research

Year:

1995

File:

PDF, 1.34 MB

1995

23

Comparable Effects of Arteriolar and Capillary Stimuli on Blood Flow in Rat Skeletal Muscle

Debra Mitchell, Jingcheng Yu, Karel Tyml

Journal:

Microvascular Research

Year:

1997

Language:

english

File:

PDF, 447 KB

english, 1997

24

Evidence for K+Channels Involvement in Capillary Sensing and for Bidirectionality in Capillary Communication

Karel Tyml, Henry Song, Patrick Munoz, Yves Ouellette

Journal:

Microvascular Research

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

25

Capillary Adrenoceptors in Rat Skeletal Muscle

Jingcheng Yu, Karel Tyml

Journal:

Microvascular Research

Year:

1997

Language:

english

File:

PDF, 157 KB

english, 1997

26

Gap Junction Uncouplers Attenuate Arteriolar Response to Distal Capillary Stimuli

Jingcheng Yu, Aurelia Bihari, Darcy Lidington, Karel Tyml

Journal:

Microvascular Research

Year:

2000

Language:

english

File:

PDF, 69 KB

english, 2000

27

A New in Vitro Model for Agonist-Induced Communication between Microvascular Endothelial Cells

Yves Ouellette, Darcy Lidington, Christian G. Naus, Karel Tyml

Journal:

Microvascular Research

Year:

2000

Language:

english

File:

PDF, 384 KB

english, 2000

28

Pulmonary Microvascular Changes during Sepsis: Evaluation Using Intravital Videomicroscopy

D.G. McCormack, S. Mehta, K. Tyml, J.A. Scott, R. Potter, M. Rohan

Journal:

Microvascular Research

Year:

2000

Language:

english

File:

PDF, 215 KB

english, 2000

29

Capillary Responsiveness to the Adenosine Analogue NECA Is Reduced in Disused Skeletal Muscle in Rats

Karel Tyml, Earl Noble

Journal:

Microvascular Research

Year:

2000

Language:

english

File:

PDF, 51 KB

english, 2000

30

Endothelin-A Receptor in Rat Skeletal Muscle Microvasculature

Debra Mitchell, Aurelia Bihari, Martin Sandig, Karel Tyml

Journal:

Microvascular Research

Year:

2002

Language:

english

File:

PDF, 105 KB

english, 2002

31

A method for on-line measurements of red cell velocity in microvessels using computerized frame-by-frame analysis of television images

Karel Tyml, Marvin H. Sherebrin

Journal:

Microvascular Research

Year:

1980

Language:

english

File:

PDF, 540 KB

english, 1980

32

Fourier transform analysis of periodic variations of red cell velocity in capillaries of resting skeletal muscle in frogs

Karel Tyml, Alan C. Groom

Journal:

Microvascular Research

Year:

1980

Language:

english

File:

PDF, 729 KB

english, 1980

33

Regulation of blood flow in individual capillaries of resting skeletal muscle in frogs

Karel Tyml, Alan C. Groom

Journal:

Microvascular Research

Year:

1980

Language:

english

File:

PDF, 708 KB

english, 1980

34

Heterogeneity of capillary diameters in skeletal muscle of the frog

R.G.A. Safranyos, C.G. Ellis, K. Tyml, A.C. Groom

Journal:

Microvascular Research

Year:

1983

Language:

english

File:

PDF, 444 KB

english, 1983

35

Temporal and spatial distributions of red cell velocity in capillaries of resting skeletal muscle, including estimates of red cell transit times

Karel Tyml, Christopher G. Ellis, Richard G. Safranyos, Scott Fraser, Alan C. Groom

Journal:

Microvascular Research

Year:

1981

Language:

english

File:

PDF, 1.29 MB

english, 1981

36

Occurrence of the “capillary contractility” phenomenon and its significance in the distribution of microvascular flow in frog skeletal muscle

Karel Tyml, Hartmut Weigelt, Dietrich W. Lübbers

Journal:

Microvascular Research

Year:

1984

Language:

english

File:

PDF, 1.22 MB

english, 1984

37

Capillary recruitment and heterogeneity of microvascular flow in skeletal muscle before and after contraction

Journal:

Microvascular Research

Year:

1986

Language:

english

File:

PDF, 1.07 MB

english, 1986

38

Quantification of red cell movement in microvessels: A new application of interactive computer graphics

C.G. Ellis, K. Tyml, W. Burgess

Journal:

Microvascular Research

Year:

1987

Language:

english

File:

PDF, 1.06 MB

english, 1987

39

Evidence for increased perfusion heterogeneity in skeletal muscle during reduced flow

Karel Tyml, Karol Mikulash

Journal:

Microvascular Research

Year:

1988

Language:

english

File:

PDF, 688 KB

english, 1988

40

Capillary as a communicating medium in the microvasculature

Hans Hubert Dietrich, Karel Tyml

Journal:

Microvascular Research

Year:

1992

Language:

english

File:

PDF, 932 KB

english, 1992

41

Microvascular response to ischemia, and tissue structure, in normal and atrophied skeletal muscle

Karel Tyml, Odile Mathieu-Costello, Claire H. Budreau

Journal:

Microvascular Research

Year:

1990

Language:

english

File:

PDF, 6.32 MB

english, 1990

42

Microvascular flow response to localized application of norepinephrine on capillaries in rat and frog skeletal muscle

Hans Hubert Dietrich, Karel Tyml

Journal:

Microvascular Research

Year:

1992

Language:

english

File:

PDF, 934 KB

english, 1992

43

Distribution of red blood cell velocity in capillary network, and endothelial ultrastructure, in aged rat skeletal muscle

Karel Tyml, Odile Mathieu-Costello, Claire H. Budreau

Journal:

Microvascular Research

Year:

1992

Language:

english

File:

PDF, 3.85 MB

english, 1992

44

Ascorbate inhibits iNOS expression in endotoxin- and IFNγ-stimulated rat skeletal muscle endothelial cells

Feng Wu, Karel Tyml, John X. Wilson

Journal:

Year:

2002

Language:

english

File:

PDF, 219 KB

english, 2002

45

Ascorbate Uptake by Microvascular Endothelial Cells of Rat Skeletal Muscle

Dr. J. X. Wilson, S. J. Dixon, J. Yu, S. Nees, K. Tyml

Journal:

Microcirculation

Year:

1996

Language:

english

File:

PDF, 1.17 MB

english, 1996

46

‘Who's who’ in renal sphaerosporids (Bivalvulida: Myxozoa) from common carp, Prussian carp and goldfish – molecular identification of cryptic species, blood stages and new members of Sphaerospora sensu stricto

HOLZER, ASTRID SIBYLLE, BARTOŠOVÁ, P., PECKOVÁ, H., TYML, T., ATKINSON, S., BARTHOLOMEW, J., SIPOS, D., ESZTERBAUER, E., DYKOVÁ, I.

Journal:

Year:

2013

Language:

english

File:

PDF, 381 KB

english, 2013

47

Myxozoa in high Arctic: Survey on the central part of Svalbard archipelago

Kodádková, Alena, Dyková, Iva, Tyml, Tomáš, Ditrich, Oleg, Fiala, Ivan

Journal:

International Journal for Parasitology: Parasites and Wildlife

Year:

2014

Language:

english

File:

PDF, 4.97 MB

english, 2014

48

Short-term effect of ascorbate on bacterial content, plasminogen activator inhibitor-1, and myeloperoxidase in septic mice

Swarbreck, Scott B., Secor, Dan, Ellis, Christopher G., Sharpe, Michael D., Wilson, John X., Tyml, Karel

Journal:

Journal of Surgical Research

Year:

2014

Language:

english

File:

PDF, 789 KB

english, 2014

49

Ascorbate Reduces Mouse Platelet Aggregation and Surface P-Selectin Expression in an Ex Vivo Model of Sepsis

Secor, Dan, Swarbreck, Scott, Ellis, Christopher G., Sharpe, Michael D., Tyml, Karel

Journal:

Microcirculation

Year:

2013

Language:

english

File:

PDF, 476 KB

english, 2013

50

Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice

Wu, Feng, Wilson, John X., Tyml, Karel

Journal:

AJP Regulatory Integrative and Comparative Physiology

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003